03.23.17
US Patent No. 9,597,274 B2; Avon Products, Inc., Suffern, NY, has patented a method for diminishing the appearance of dermatological signs of aging that entails topically applying a compposition to the skin. The composition, in topically acceptable vehicle, contains active agent comprising a GDF-11 peptide fragment consisting of the sequence LRLK (SEQ ID NO: 453), MVV (SEQ ID NO: 369), or QILSKLRL (SEQ ID NO: 2028), and/or C1-24 aliphatic derivatives thereof.