Formulary

Improved Acne Appearance Cream

October 1, 2008


Phase A
Estol 3650 (Uniqema) (Glyceryl myristate)
1.50
Lanette 16 (Cognis Deustschland GmbH) (Cetyl alcohol)
1.50
Finsolv TN (Innospec Active Chemicals) (C12-15 alkyl benzoate)
4.00
Phenonip (Clariant GmbH) (Phenoxyethanol and methylparaben and ethylparaben and butylparaben and propylparaben and isobutylparaben)
0.80
Lanol 99 (Seppic) (Isononyl isononanoate)
2.00
Brij 72 (Uniqema) (Steareth-2)
1.50
Brij 721 (Uniqema) (Steareth-21)
1.50
Glycerin (Cognis)
3.00
Edeta BD (BASF) (Disodium EDTA)
0.10
Keltrol CG-T (CP Kelco) (Xanthan gum)
0.30
Carbopol Ultrez 21 (Noveon) (Acrylates/C10-30 alkyl acrylate crosspolymer)
0.25
Water dem.
68.00
STAY-C 50 (DSM Nutritional Products) (Sodium ascorbyl phosphate)
3.00
Natriumdisulfit (Merck KGaA) (Sodium metabisulfite)
0.05

Phase B
1,3-Butylenglykol (Merck KGaA) (Butylene glycol)
2.00

Phase C
Water dem.
10.00

Phase D
Citric Acid, Anhydrous (Fluke Chemie)
0.50

Procedure
Heat phase A up to 85°C; and heat also phase B up to 85°C. When both have the same temperature add phase B to phase A while homogenizing intensively. Cool down the product to 35°C while stirring. Add phase C and D homogenize intensively again. It is generally recommended to use vacuum while producing the emulsion.

Properties
pH:     7.26
Viscosity:     10320 cps
(Brookfield, RV 5, 10 rpm)

More Information
DSM Nutritional Products, 45 Waterview Blvd., Parsippany, NJ 07054
(973) 257-8501, Fax: (973) 257-8580, Website: www.nutraaccess.com
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