Formulary

Centerchem Formulates Therapeutic Cream

July 1, 2009


Phase A
Deionized water
56.85
Sodium hydroxide (10% solution)
56.85
Disodium EDTA
0.10
RITA Glycerin USP (RITA) (Glycerin)
3.00
Keltrol CG-RD (CP Kelco) (Xanthan gum)
0.10
Tego Care 165 (Evonik Industries) (Glyceryl stearate & PEG-100 stearate)
6.00
Isopropyl palmitate
4.00
Hazelnut oil (Provital/Centerchem)
1.50
Macadamia oil (Provital/Centerchem)
1.50
Petalatum (Centerchem)
12.00
PEG-8 Beeswax (Koster Keunen)
1.50
Tego Alkanol 1618 (Evonik) (Cetearyl alcohol)
2.50
Microcrystalline wax 170/180 (Koster Keunen)
3.00
Dow Corning 245 Fluid (Dow Corning) (Cyclopentasiloxane)
4.00

Phase B
Keltrol CG-RD (CP Kelco) (Xanthan gum)
0.10

Phase C
Diocide (Centerchem)
0.70

Procedure
Combine phase B ingredients and begin heating in water bath to 75°C. Add NaOH and EDTA to phase A water. Begin heating to 75°C. At 55°C, add xanthan gum and glycerin to water phase. Mix until uniform. When both phases have reached 75°C, slowly add phase B to phase A. Mix for 10 minutes. Cool. At 55°C, add phase C ingredients. Mix until uniform. Continue cooling. Pour into containers while still warm.

More Information
Centerchem, Inc., Tel: (203) 822-9800, Website: www.centerchem.com
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