Formulary

Soothing Hand Sanitizing Gel

December 1, 2009


Phase A
Deionized water
37.59
SilSense Copolyol-1 (Lubrizol/Noveon) (PEG-33 (and) PEG-8 dimethicone (and) PEG-14)
0.30
Carbopol Ultrez 21 Polymer (Lubrizol/Noveon) (Acrylates/C10-30 alkyl acrylate crosspolymer)
0.25
Propylene glycol (Conjunto Lar)
0.50
Alcohol, ethanol, absolute, 96 wt% (Conjunto Lar)
60.00
FD&C Blue 1 (0.1% solution) (Emerald Perf. Materials)
0.05
Ozonic FR-511353 (Robertet) (Fragrance)
0.15

Phase B
Hydramol (Lubrizol/Noveon) PGPL Ester (PEG/PPG-8/3 laurate)
1.00

Phase C
AMP-95 (Dow Chemical) (Aminomethyl propanol)
0.16

Procedure
Phase A—In a suitable vessel add SilSense Copolyol-1 Silicone to warm (25-40°C) deionized water.  Mix until clear and uniform. Stop agitation. Sprinkle Carbopol Ultrez 21 polymer onto the surface of deionized water. Wait until the polymer has completely “wet out.”  Begin gentle agitation (200 rpm) for 5 minutes. Add the remaining ingredients of phase A in the order listed and mix well. Add Hydramol PGPL Ester with mixing.  Mix until uniform. Neutralize batch with AMP-95 with mixing.  Mix until uniform. Add the ingredients 8-9 to batch with mixing.  Mix until uniform.

Properties
Appearance—Clear blue semi-viscous gel; pH—6.5–7.5; Viscosity (mPa·s)—6,900–9,700 (Brookfield RVDV-II+ PRO @ 20 rpm, 25°C, #5 spindle); Recommended Packaging—PET bottle or sachets; Stability—Passed 3 months @ 45°C, 4 cycles freeze/thaw.

More Information
Due to the alcohol in this formulation, follow safety precautions appropriate for the handling of flammable liquids. Hand sanitizing gels may be regulated as drug products. Review your country’s regulations to insure compliance.

More Information
Lubrizol Advanced Materials Inc. (Noveon Consumer Specialties); Tel: (216) 447-5000, (800) 379-5389; Website: www.personalcare.noveon.com
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