Formulary

Skin Lightening Cream Gel with Alpha-Arbutin and DISMUTIN®-PF

December 1, 2010


Phase A
Ethylhexyl Isononanoate (Pelemol 89/Phoenix Chemicals)
5.00
Isohexadecane (Arlamol HD/Uniqema)
2.00
Diethylhexyl Carbonate (Tegosoft DEC/Evonik)
5.00
Dimethicone (DC200fluid/200cts/Dow Corning)
1.00

Phase B
Ammonium Acryloyldimethyltaurate & VP Copolymer (Arisoflex AVC/Clariant)
1.20

Phase C
Deionized Water
68.90
Glycerin (Rita Glycerin USP/Rita)
5.00
DISMUTIN-PF
0.20
DIOCIDE
0.70

Phase D
Deionized Water
10.00
ALPHA-ARBUTIN
1.00

Phase E
Citric Acid (10% solution)
q.s. to pH 5

Procedure
1. Mix Phase A together. Add Phase B to Phase A, mix until homogeneous.
2. Mix together Phase C.
3. Premix Phase D ingredients and add to Phase C.
4. Add Phase C/D to Phase A/B. Homogenize to obtain a homogenous cream gel.

More Information
Centerchem, Inc.
(203) 822-9800
www.centerchem.com

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