Online Exclusives

Plastic Surgery? No Thanks

January 7, 2009

CellCeuticals Biomedical Skin Treatments provide an alternative to invasive procedures.

Plastic Surgery? No Thanks!

CellCeuticals Biomedical Skin Treatments provide an alternative to invasive procedures.

By Joanna Cosgrove
Online Editor

Anti-aging skin care treatments account for the fastest growing segment within the skincare category with an increase of 67 percent from 2002 to 2007 to reach $14.9 billion (Euromonitor International). In the same vein, plastic surgery procedures increased seven percent from 2006 to 2007, however not all consumers are good candidates for cosmetic surgery, preferring a less invasive approach to maintain a youthful appearance. To that end, board certified plastic surgeon, Dr. Garth Fisher, and beauty industry veteran, Paul Scott Premo, combined their extensive expertise and experience to create CellCeuticals Biomedical Skin Treatments, a system that integrates the latest advances in biotechnology and medical science into bio-treatments that target the underlying source of cellular skin aging and help re-create visibly younger skin.

Not ready for plastic surgery? Then be sure to try CellCeuticals.
“People are always surprised to hear that I turn away 40 percent of those who walk into my office because either they are not a candidate for procedures, have unrealistic expectations, or simply their skin is not in an optimal condition for procedures,” commented Dr. Fisher. “Now, with the introduction of CellCeuticals, I am able to offer a clinically effective skin treatment system for those who are not ready for plastic surgery.” 

Dr. Fisher went on to explain that while traditional procedures such as facelifts, brow lifts and eyelid surgery among others, remove excess skin and shift tissue to a more youthful location, they cannot, however, improve the quality of the skin (i.e. tone, firmness, radiance, elasticity, texture, density, smoothness, pigmentation, hydration, pore size, etc.). Laser procedures, dermabrasion and chemical peels can change the quality of the skin, but as invasive procedures, they also come with inherent risk, cost and downtime. “I always try to advise the least invasive, least expensive and least risky option first to my patients to help satisfy their needs,” he said. “Effective skin care products are part of this philosophy.”

Effective skin care products are also the prescription for patients who are deemed “higher risk,” including those with darker pigmented skin and medical problems such as diabetes. “Some patients with thin crepe skin around the lower eyelids really benefit from effective skin care treatments that can actually thicken the skin in this area,” he said. “The increased density of tissue really helps improve the appearance of their eyes! In many cases, patients with skin fitting this description are better suited for skin care products than cosmetic surgery.”

Next Generation Lipopeptides

While surgery is not for everyone, taking care of one’s skin should be part of every person’s daily regimen. “I know first hand that savvy customers expect more than a ‘glorified miracle in a bottle’ and ‘empty promises,’” said Mr. Premo, whose past skin care company affiliations span Allergan, Chanel, MD Formulations/ MD Forte and Murad. “They’re frustrated with unrealistic claims. They want products that deliver their promised results.”

To that end, the marquis ingredient used in CellCeuticals’ CellGenesis Regenerative Skin Treatment product is GFP (Growth Factor Peptide) Cellular Complex. GFP Cellular Complex is described as a combination of lipopeptides, retinol and antioxidants in a proprietary nanoemulsion delivery system. The ingredient “performs as a cellular stimulant to encourage cellular regeneration,” said Dr. Fisher, who added that it was designed to facilitate a “proliferation response” and eliminate the “inflammatory response” common with other anti-aging ingredients and procedures.

“The CellCeuticals GFP Cellular Complex is the culmination of twelve to fifteen years of research in new states of matter and delivery technologies designed to target cellular skin aging,” noted Dr. Fisher.

CellCeuticals’ patent-pending, bioengineered lipopeptides are synthesized and tested using state-of-the-art DNA Microarrays and represent the “next generation” of peptides. “Many first-generation peptides not only increase expression of genes that code for elastin and collagen but also increase the expression of genes that code for Matrix Metalloproteinases (MMPs), enzymes that breakdown the extracellular matrix of the skin,” said Dr. Fisher. “In addition, some of these peptides increase expression of the interleukin genes involved in the inflammatory cascade.”

The company’s lipopeptides are targeted to “increase expression of certain genes (elastin, collagen) and to decrease others (MMPs and interleukins.)” An additional, unexpected and surprising property of the lipopeptides, according to CellCeuticals, is their broad-spectrum anti-microbial properties, making them “ideal candidates” for anti-acne products. The GFP Cellular Complex triggers cellular stimulation to encourage the regeneration of vital proteins responsible for firmer, thicker and youthful looking skin.

To confirm the results of GFP Cellular Complex, CellCeuticals submitted the product to Stephens & Associates, which conducted the extensive eight-week, “independent and objective” clinical study with 70 subjects having mild to moderate periocular fine lines and wrinkles and the presence of mild to moderate dyschromia (discoloration). Under the direction of Chief Science Investigator Dr. Thomas Stephens, the results of the clinical study concluded the CellCeuticals Skin Treatments System with GFP Cellular Complex was proven to diminish visible wrinkles by 36 percent, decrease the appearance of the deepest wrinkle depth by 45 percent, renew skin smoothness by 64 percent, refine skin texture by 31 percent and reveal skin radiance by 33 percent. Skin tone, firmness, moisture and redness were also favorably benefitted.

“Significant improvements in all clinical grading parameters were seen as early as week two,” said Dr. Fisher. “After eight weeks of usage, the regimen produced the following percent changes in various clinical parameters: bioinstrumentation measurements showed the regimen produced a 48.2 percent increase in skin hydration (Corneometer), a 26.8 percent increase in skin density (ultrasound measurements) and a 20.2 percent improvement in skin firmness (i.e., decreased extensibility, measured by Cutometer). The combination of Corneometer, ultrasound and Cutometer data suggests that the regimen remodels photodamaged skin so that the skin appears firmer, denser, and more hydrated.

Furthermore, “self-assessment questionnaires reported 100 percent of subjects agreed their skin was smoother, 93 percent agreed skin felt more elastic, 83 percent agreed fine lines and wrinkles appeared minimized, 86 percent agreed skin looked clearer, and 90 percent agreed skin looked healthier,” added Dr. Fisher.

The six-product line is comprised of Extremely Gentle Skin Cleanser ($35, 6.7 fluid oz.); Extreme Defense Anti-Cell Damage Skin Treatment ($65, one fluid oz. airless pump), an antioxidant-rich day treatment that helps defend skin against age-promoting free radicals; CellGenesis Regenerative Skin Treatment ($80, one fluid oz. airless pump), a potent night treatment containing GFP Cellular Complex; NeoCell Micro-Resurfacing Skin Treatment ($45, two fl oz.), a weekly gentle skin resurfacer containing natural enzymes and volcanic micro-minerals; and CerActive Active Moisture + Barrier Repair Skin Treatment ($45, two fluid oz.), a deep penetrating moisture and barrier repair treatment formulated to soothe skin and provide long-lasting skin hydration.

Not only has each CellCeuticals Skin Treatment product undergone testing to substantiate product performance and safety, the products are also fragrance- and artificial color free, paraben-free, phthalate-free, non-comedogenic and are sodium lauryl sulfate–free.

The CellCeuticals Biomedical Skin Treatments collection will launch through a multi-channel distribution strategy beginning with direct response television and e-commerce at in January 2009. National and international retail distribution is planned for 2010.

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