Arch Personal Care Products’ Metabiotics Resveratrol is a biotechnological ingredient for use in anti-aging skin creams and related products. The new material is produced through the fermentation of the small molecule, resveratrol, with the microorganism, Pichia pastoris. According to Arch, the resulting biofermentation extract completely metabolizes the resveratrol, affording anti-inflammatory and Collagen IV synthesis activity to target micro-inflammation and maintain the structural integrity of skin cells through the dermal epidermal junction.
In vitro studies were performed to determine the inhibitory benefits of Metabiotics Resveratrol on a full thickness tissue model to reduce expression of the anti-inflammatory enzyme cyclooxygenase 1 [COX1] along with its ability to promote the synthesis of Collagen IVA on the same tissue model. The results, in both cases, confirm with statistical significance that either a 1% or 2% treatment of Metabiotics Resveratrol reduces the levels of the COX1 enzyme and increases the amount of COLL IVA synthesis, according to Arch. In vivo, an anti-aging study has confirmed a reduction in fine lines and wrinkles following a 28-day application, as well as firming and lifting of the skin to reduce notable sagging that was present prior to treatment.
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