Formulary

Anti-Glycation Lotion with Dglyage and Lipochroman-6

Released by Centerchem Inc

December 1, 2010


Phase A
Deionized water
74.12
Ultrez 10 (Lubrizol) (Carbomer)
0.20
Hispagel 200 NS (Cognis/Centerchem)
5.00

Phase B
Promulgen D (Lubrizol) (Cetearyl alcohol & ceteareth-20)
2.00
Cutina GMS-SE (Cognis) (Glyceryl stearate)
1.25
Myrj 59 (Uniqema) (PEG-100 stearate)
1.00
Schercemol DIA Ester (Lubrizol) (Diisopropyl adipate)
3.00
Organza (Centerchem)
8.00

Phase C
Sodium hydroxide (10% solution)
0.70

Phase D
Diocide (Centerchem)
0.70
Dglyage (Lipotec/Centerchem)
3.00

Phase E
Lipochroman-6 (Lipotec/Centerchem)
0.03
Tegosoft TN2 (Evonik) (C12-15 alkyl benzoate)
1.00

Procedure
Disperse carbomer in water, mix until uniform. Add remaining phase A ingredients, heat to 80°C. Heat phase B to 80°C. Add phase B to phase A under moderate mixing. Mix for 10 minutes. Begin cool down. At 50°C, add phase C (batch should be ~ pH 5.5u20136.5). At 40°C, add phase D ingredients one at a time. Mix until uniform. Premix phase E, add to batch. Mix until uniform. Discontinue.

More Information
Centerchem, Inc.
(203) 822-9800
www.centerchem.com

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