Cream Stimulates Mitochondrial Activity
• US 8,435,547 B2; John P. Blass of New York City has patented a topical skin composition for stimulating mitochondrial activity in the skin cells of humans. It is comprised of (a) a Krebs cycle intermediate, a precursor of a Krebs cycle intermediate, or a combination thereof, comprising diethylhexyl malate; (b) a pharmaceutically acceptable topical vehicle comprising a mitochondrial fuel or substance that is efficiently convertible to mitochondrial fuel by normal skin cell metabolism comprising tristearyl glycerol, and (c) at least one antioxidant selected from the group consisting of undutched raw chocolate, green tea and resveratrol. The combination of (a), (b) and (c) is in an amount effective to stimulate mitochondrial activity in skin cells of humans when administered to skin regions in need.
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