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L’Oréal Combats Melanocytes Disappearance in Hair

July 10, 2013

• US Patent No. 8,445,004 B2; L’Oréal, Paris, has patented a  method for combating the disappearance of the melanocytes of hair follicles by maintaining and/or by regenerating the population of active melanocytes of the bulbs and of the quiescent melanocytes of the upper region of hair follicles. It is comprised of topical administration of EUK-8, 21-aminosteroids, or putrescine for such period of time as required to elicit the desired effect, a thus effective amount of at least one active agent mimicking DOPAchrome tautomerase activity selected from the group consisting of EUK-8, 21-aminsteroids or putrescine.