Safety Assessment In Skin Care


  • Testing

    Selecting In Vitro Test Models: Monolayers to Skin Explants

    Cells emerged on earth at least 3.5 billion years ago, but it took humanity quite some time to discover and then explore these magical structural units. Cells were discovered in 1665 by Robert Hooke, an English natural philosopher, architect and math…
    Nava Dayan, Dr. Nava Dayan LLC 11.02.16

  • Actives | Functional Ingredients | Skin Care | Testing

    Endocrine Disruption & Cosmetic Ingredients

    Testing for endocrine disruption aims to identify the potential of a compound to disrupt the endocrine system. Endocrine disruptors are compounds that interfere with components of the endocrine system, which includes the glands in the body that produ…
    Nava Dayan, Dr. Nava Dayan LLC 07.01.16

  • Testing for Eye Irritation

    Testing for Eye Irritation

    Take a closer look at three test methods.
    Nava Dayan, Dr. Nava Dayan LLC 05.02.16

  • Testing for Genotoxicity

    Genotoxicity is defined as the modification of the genetic information in a living cell. It establishes the potential of a compound or mixture to damage the cellular genetic information thereby its likelihood to trigger mutations that may l…
    Nava Dayan, Dr. Nava Dayan LLC 03.01.16

  • Actives | Functional Ingredients | OTC/Medicated  | Polymers | Preservatives | Skin Care | Surfactants | Testing

    Assessment of Potential Skin Sensitization

    Anaphylaxis to skin care products is possible.
    Nava Dayan, Dr. Nava Dayan LLC 01.04.16

  • Test Your Cosmetic Formulas For Photo-Toxicity Reactions

    Photo-toxicity reaction occurs when a biological tissue is exposed to a chemical entity which, when accompanied with radiation, becomes toxic. As such, only body organs that may be directly exposed to radiation, such as skin and eyes, are potential t…
    Nava Dayan, Dr. Nava Dayan LLC 11.02.15

  • Skin Corrosion & Primary Irritation

    Skin corrosion is defined as irreversible damage to the skin following the application of a substance. When it contacts the tissue, a corrosive compound generates necrosis through the epidermis and the dermis with ulcers and bleeding. The healing pro…
    Nava Dayan, Dr. Nava Dayan LLC 09.01.15

  • Cytotoxicity Is Critical In Cell Culture Study

    A cell culture must be viable and functioning in order to assess the biological activity and effect of compounds and formulations on activity. This means that prior to any such study, one must understand the impact of the tested compound on the viabi…
    Nava Dayan, Dr. Nava Dayan LLC 07.01.15

  • Solids and Nanoparticles Interactions with Skin

    Solids and Nanoparticles Interactions with Skin

    Many compounds incorporated into topical formulations are in their solid particulate form. Examples include zinc oxide in diaper rush ointment and in calamine lotion for chicken pox, sunscreens containing both titanium and zinc oxide and more as well…
    Nava Dayan, Dr. Nava Dayan LLC 05.01.15

  • Absorption’s Key Role In Safety Assessment

    Beautifying the appearance of the skin by merely covering it, thereby minimizing the appearance of superficial imperfections, became just another stream in the flood of compounds that are presented by suppliers in the skin care industry. The majority…
    Nava Dayan, Dr. Nava Dayan LLC 03.04.15

  • Actives | Functional Ingredients | OTC/Medicated  | Skin Care
    Physical Chemical Properties in Safety Assessment

    Physical Chemical Properties in Safety Assessment

    The first section on the guidelines published in October 2012 by The Organization for Economic Co-operation and Development (OECD) for testing of chemicals includes a list of relevant physical-chemical properties.1 Identification of the composition o…
    Nava Dayan, Dr. Nava Dayan LLC 01.06.15