03.18.09
Demand for plumper lips is a growing phenomenon as women with naturally fine lips wish to give them more sensuality. Furthermore with age, women try to retrieve attractive lips, which have lost their contour and definition, because of dryness, loss in volume and ptosis, and decrease in derma density.
For this reason, Sederma (stand no. E500) has developed Volulip an active substance containing a plant Portulaca extract, which is associated with a natural modified matrikine-mimetic peptide, whose main activity is to stimulate hyaluronic acid synthesis.
In order to demonstrate the product efficacy and its mechanism of action, several in vitro tests have been carried out following 3 axes, stimulation of dermal matrix molecules (collagen 1, collagen 3, fibronectin, HSP47), reinforcement of DEJ molecules (collagen 4, laminin 5), improvement of hydric sphere (hyaluronic acid, aquaporin 3).
Sederma also carried out two clinical studies to prove Volulip efficacy on youth, hydration and lip volume. The first one involved 29 panelists with a twice daily application of a balm containing 1% Volulip for a month. It associated several complementary methods such as Aeroflexmete, fringe projections (FOITS) and MoistureMeter-D.
The second one was carried out on a total of 21 panelists to measure re-densification with an ultrasonor echograph. The results are very significant. We observed a gain of firmness (+13.3%), hydration (+50.6%), softness (10.5%), volume (+15.1%), curvature (+9.2%) and an increase (+19.6%) of the surface of the central area of the lower lip for volunteers with very fine lips.
More info: Sederma SAS, Tel: + 33 1 34 84 10 10, E-mail: sederma@sederma.fr, Website: www.sederma.fr
For this reason, Sederma (stand no. E500) has developed Volulip an active substance containing a plant Portulaca extract, which is associated with a natural modified matrikine-mimetic peptide, whose main activity is to stimulate hyaluronic acid synthesis.
In order to demonstrate the product efficacy and its mechanism of action, several in vitro tests have been carried out following 3 axes, stimulation of dermal matrix molecules (collagen 1, collagen 3, fibronectin, HSP47), reinforcement of DEJ molecules (collagen 4, laminin 5), improvement of hydric sphere (hyaluronic acid, aquaporin 3).
Sederma also carried out two clinical studies to prove Volulip efficacy on youth, hydration and lip volume. The first one involved 29 panelists with a twice daily application of a balm containing 1% Volulip for a month. It associated several complementary methods such as Aeroflexmete, fringe projections (FOITS) and MoistureMeter-D.
The second one was carried out on a total of 21 panelists to measure re-densification with an ultrasonor echograph. The results are very significant. We observed a gain of firmness (+13.3%), hydration (+50.6%), softness (10.5%), volume (+15.1%), curvature (+9.2%) and an increase (+19.6%) of the surface of the central area of the lower lip for volunteers with very fine lips.
More info: Sederma SAS, Tel: + 33 1 34 84 10 10, E-mail: sederma@sederma.fr, Website: www.sederma.fr