05.18.09
Lipo Chemicals, Inc., Paterson, NJ, featured two novel anti-inflammatory agents during the New York SCC Supplier’s Day: Gorgonian Extract GC (INCI: Caprylic/Capric Triglyceride (and) Sea Whip Extract) and Gorgonian Extract PTG (INCI: Pentylene glycol (and) sea whip extract).
According to Lipo, Gorgonian Extract is a natural anti-inflammatory ingredient that is safe, effective, and
environmentally friendly. It is an extract from the marine organism Pseudopterogoria elisabethae (sea
whip), a renewable resource harvested from the Caribbean Sea, which consist primarily of powerful
anti-inflammatory compounds called pseudopterosins.
The anti-inflammatory properties of pseudopterosins are well documented in scientific literature, according to Lipo.
Pseudopterosins have been shown to inhibit the production of inflammatory mediators. This
activity has been assayed both in vitro and in vivo. The in vitro enzymatic assay measures inhibition
of phospholipase A2 (PLA2). This enzyme cleaves arachidonic acid from the cell membrane and
makes it available for enzymatic reactions and is the initial enzyme in the arachidonic pathway that
ultimately leads to the synthesis of eicosanoids, the inflammation mediators. These molecules play
an important role in inflammation.
In a study performed to learn the concentration-activity relationships of the pseudopterosin mixture in a unicellular aquatic cellular protist, tetrahymena, a direct correlation was demonstrated between the concentration of the mixture and anti-inflammatory activity. Therefore, the percentage of use in formulas will correlate with the activity needed to be achieved. Gorgonian Extract is ideal for a variety of elegant, effective skin care and treatment products having a pH range of 4 to 7.
More info: Lipo Chemicals, Inc., Paterson, NJ Tel:(973) 345-8600; Website: www.lipochemicals.com
According to Lipo, Gorgonian Extract is a natural anti-inflammatory ingredient that is safe, effective, and
environmentally friendly. It is an extract from the marine organism Pseudopterogoria elisabethae (sea
whip), a renewable resource harvested from the Caribbean Sea, which consist primarily of powerful
anti-inflammatory compounds called pseudopterosins.
The anti-inflammatory properties of pseudopterosins are well documented in scientific literature, according to Lipo.
Pseudopterosins have been shown to inhibit the production of inflammatory mediators. This
activity has been assayed both in vitro and in vivo. The in vitro enzymatic assay measures inhibition
of phospholipase A2 (PLA2). This enzyme cleaves arachidonic acid from the cell membrane and
makes it available for enzymatic reactions and is the initial enzyme in the arachidonic pathway that
ultimately leads to the synthesis of eicosanoids, the inflammation mediators. These molecules play
an important role in inflammation.
In a study performed to learn the concentration-activity relationships of the pseudopterosin mixture in a unicellular aquatic cellular protist, tetrahymena, a direct correlation was demonstrated between the concentration of the mixture and anti-inflammatory activity. Therefore, the percentage of use in formulas will correlate with the activity needed to be achieved. Gorgonian Extract is ideal for a variety of elegant, effective skin care and treatment products having a pH range of 4 to 7.
More info: Lipo Chemicals, Inc., Paterson, NJ Tel:(973) 345-8600; Website: www.lipochemicals.com