US Patent No. 9,974,729 B2
; Mary Kay Inc.
, Addison, TX, has patented a skin treatment method and composition. It entails applying a topical composition comprising saccharide isomerate, hydrolyzed algin, zinc sulfate, and a dermatologically acceptable vehicle to skin, wherein at least one of filaggrin production is increased, skin moisture is increased, occludin production is increased, TNFa production is inhibited, oxidative damage is prevented, PPAR-y activity is inhibited, MMP1 is inhibited, MMP9 is inhibited, or elastase is inhibited.
The saccharide isomerate comprises an exopolysaccharide synthesized by Vibrio alginolyticus, and the hydrolyzed algin extract comprises an anionic polysaccharide synthesized by Laminaria digitate.
The composition contains saccharide isomerate, hydrolyzed algin, and zinc sulfate.