Microbiota Gets Imbalanced with Aging
Silab research focuses on Caucasian women.
The cutaneous microbiota of Caucasian women becomes imbalanced with aging, according to a recent Silab
study published in the peer-reviewed Journal of Applied Microbiology.1
Facial skin samplings were taken from young and old Caucasian women and were analyzed by Silab’s researchers using their high-tech MiSeq tool. Bioinformatic analysis of the data showed that the distribution of the microbiota changes in the course of aging.
“Previous studies on Asian women had shown a change in the cutaneous microbiota in the course of aging. Nevertheless, given that each population has a different microbial signature with its own lifestyle, it was of interest to the scientific community to decrypt the imbalances of the age-related cutaneous microbiota specifically in Caucasian women” stated Romain Jugé, Silab’s R&D project leader.
Based on this scientific finding, future anti-aging cosmetic care products can contain active ingredients that restore the balance of the microbiota of mature skin.
The results of these modeling studies in vivo led to the selection of panels of volunteers and the substantiation by metasequencing of Ecobiotys, which Silab calls the first active ingredient bio-inspired by the high regulating capacity of floral nectar microbiota: the Nectarobiota. Obtained from the yeast Metschnikowia reukaufii, isolated from the nectar of the porcelain flower Hoya carnosa, Ecobiotys specifically rebalances the distribution of bacterial communities of mature skin by strengthening the skin’s immune and mechanical barriers. The quality of the skin barrier its thereby improved and the complexion is enhanced.
 Romain Jugé, Pauline Rouaud-Tinguely, Josselin Breugnot, Katia Servaes, Skin microbiota facial sampling by swabbing. Christine Grimaldi, Marie-Paule Roth, Hélène Coppin,Brigitte Closs, Journal
of Applied Microbiology, 2018 Sep; 125(3):907-916.