04.18.19
US Patent No. 10,231,907 B2: Algenist Holdings, Westport, CT, has patented a gel, lotion, cream or ointment composition suitable for topical administration that contains microalgal exopolysaccharide particles. The exopolysaccharide is produced by microalgae of the genus Parachlorella. The exopolysaccharide particles are made by culturing microalgae cells in a culture medium so that exopolysaccharide is secreted by the microalgal cells into the culture medium; separating the exopolysaccharide from the microalgal cells to create a purified exopolysaccharide; heating, in two parts, the purified exopolysaccharide as to render it partially insoluble in water, and so that it forms a polysaccharide gel in water; and generating particles from the heated exopolysaccharide that increase in volume on contact with water by at least 100% compared to their anhydrous volume; and the particles increase in volume for at least 4 hours. The composition ,when applied to mammalian skin, reduces the presence of crow's feet fine lines/wrinkles, increases skin elasticity, increases skin moisture, or decreases transepidermal water loss.