09.28.21
The use of natural phytochemicals in topical formulations with the clinical ability to protect, maintain and restore skin’s appearance and architecture throughout life are important to consumers in today's anti-aging marketplace.
In recent research, Sytheon chronicles the extraordinary anti-aging skin benefits of Synastol TC prepared from the fruits of Terminalia chebula, an Asian herb steeped in traditional medicine and revered for its healing powers.
The study revealed that Synastol TC exhibited longer-lasting and more efficient antioxidant neutralization of reactive oxygen species (ROS) than α-tocopherol, and safeguarded keratinocytes against increases in intracellular ROS, inflammatory cytokines (IL-6 and IL-8) and peroxidation of membrane lipids following exposure to particulate matter for up to three hours.
In an eight-week clinical trial on female subjects who had lived at least five years in Bangalore, one of the highest polluted cities in India, there were significant benefits observed using 1% Synastol TC lotion to the whole face. The trial yielded significant improvements in dermatologist scores and subject self-assessments for skin texture, hydration, tone, firmness and radiance, compared with its placebo. Self-perceived improvements by subjects drove compliance over the course of the study.
Unlike many phytochemical extracts, Synastol TC is produced using a well-defined proprietary manufacturing process that guarantees standardized levels of the bioactive phytochemicals (70% hydrolysable tannins, including greater or equivalent to 20% chebulinic and greater or equivalent to 15% chebulagic acids) known to account for its biological properties. This consistency in manufacturing ensures reproducibility of skin benefits provided by Synastol TC with every manufactured batch.
Immediate and long-lasting benefits of Synastol TC align with the minimalist approach of applying one application each morning to combat external aggressors throughout the day while continuing to provide reparative and strengthening skin care benefits throughout the night.