05.13.22
US Patent No. 11,324,679 B2 (Anjing Lou, Teanoosh Moaddel, Anil Babubhai Patel); Conopco, Inc., Englewood Cliffs, NJ, has patented a method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors. The composition has a retinoic acid precursor and a resorcinol to impede oxidation of the precursor in situ in the composition. The composition comprised of a retinoic acid precursor, meaning a component that, when oxidized, can convert to retinoic acid, wherein the retinoic acid precursor is selected from retinyl propionate, hydroxyanasatil retinoate, and mixtures thereof; a skin benefit agent comprising resorcinol and/or a derivative thereof, wherein the derivative has at least one H on the ring structure and/or on a hydroxy group of the resorcinol replaced with an alkyl group, wherein the skin benefit agent comprising resorcinol and/or derivative thereof is selected from 4-ethyl resorcinol, 4-butyl resorcinol, 4-hexyl resorcinol, 4-isopropyl resorcinol and mixtures thereof; and a cosmetically acceptable carrier wherein the retinoic acid precursor and the skin benefit agent comprising resorcinol and/or a derivative thereof are present at a weight ratio of from about 1:2 to about 2:1. The patent also entails a method for impeding oxidation of a retinoic acid precursor in a composition comprising the step of combining the retinoic acid precursor with a skin benefit agent comprising resorcinol and/or derivative thereof wherein the retinoic acid precursor is selected from retinyl propionate, hydroxyanasatil retinoate, and mixtures thereof and the skin benefit agent is selected from 4-ethyl resorcinol, 4-butyl resorcinol, 4-hexyl resorcinol, 4-isopropyl resorcinol and mixtures thereof, wherein the retinoic acid precursor and the skin benefit agent comprising resorcinol and/or a derivative thereof are present at a weight ratio of from about 1:2 to about 2:1.