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    Barriers to Entry?

    Skin normally does a good job keeping things out; but atopic dermatitis and other maladies compromise the stratum corneum.

    Barriers to Entry?
    Symposium Chair Carine Mainzer, Silab (left) and NYSCC Chair Cathy Piterski, Givaudan Active Beauty.
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    Tom Branna, Editorial Director11.21.18
    Skin isn’t just the largest organ in the body, it’s one of the hardest working; performing myriad tasks such as regulating temperature, eliminating waste, and protecting the body from injury. The New York Society of Cosmetic Chemists’ symposium, Skin Barrier Disruption & Inflammation, was sponsored by Silab, Inc. Carine Mainzer, PhD, scientific support manager, Silab Inc., chaired the event and served as the first presenter, answering the question: "Upon barrier breakage and bacterial invasion, how do skin cells communicate to immune effectors?"


    Mainzer reviewed the biology of skin, the skin barrier’s function and its disruption and the skin’s defenses. Some of the triggers for skin barrier problems include genetic factors, wounds, allergies, inflammation, seasonal humidity, age, fair pigmentation and even psychological stress.


    "Indeed, the skin is a dynamic barrier that interacts and senses its environment," noted Mainzer. "Upon barrier breakage, the skin orchestrates a defense response that enables signaling the damage and the danger to surro

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