• Login
    • Join
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Formulary
    • Exclusives
    • Top Companies
    • Raw Materials
    • End-User
    • Packaging
    • Directories
    • Events
    • Jobs
    • More
  • Magazine
  • News
  • Formulary
  • Exclusives
  • Top Companies
  • Raw Materials
  • End-User
  • Packaging
  • Directories
  • Events
  • Jobs
  • Current / Back Issues
    Features
    Columns
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    In Sickness & in Health

    In Action

    Tress Test

    From Hollywood to Hair Color

    Virtual Reality for Makeup Is Not Make Believe
    Online Exclusives
    Association News
    Breaking News
    Financial News
    Industry News
    International
    Marketing News
    New Products
    News Front
    Packaging News
    Patents
    Personnel
    Regulations
    Snapshots
    Top News
    Live From Shows
    Top News
    Birchbox Partners with Buzzfeed

    Coty Strengthens Its Leadership

    Jennifer Garner Joins Virtue Labs

    Perfect Corp. Partners with Sally Beauty

    Dollar General To Sell CBD Beauty
    Blog
    Online Exclusives
    Infographics
    Podcasts
    Whitepapers
    Videos
    Expert's Opinion
    eBook
    Surveys
    International Top 30 Report
    Top 50 Report
    Top Companies
    6. Johnson & Johnson

    7. Ecolab

    The International Top 30

    15. Sun Products

    22. Zep
    Actives
    Functional Ingredients
    Pigments
    Polymers
    Preservatives
    Surfactants

    Givaudan Unveils RitualEssenz Brazil

    Where Angels Soar

    Croda Awarded for Reputation

    DSM and Metex Nøøvista Collaborate

    FDA May Change Manufacturing Survey
    Air Care/Environmental Fragrance
    AP/Deo
    Color Cosmetics
    Disinfectants
    Fine Fragrance
    Hair Care
    Household Cleaning
    I&I Marketplace
    Laundry Care
    Oral Care
    OTC/Medicated
    Packaging
    Personal Cleansers
    Skin Care
    Sun Care
    Testing

    Birchbox Partners with Buzzfeed

    Coty Strengthens Its Leadership

    Jennifer Garner Joins Virtue Labs

    Perfect Corp. Partners with Sally Beauty

    Dollar General To Sell CBD Beauty
    Lab Equipment
    Mixing
    Packaging
    Testing

    Seven of the Best Ideas in Beauty Sustainability

    Love Beauty and Planet Addresses Waste

    A New Era in Efficacy Testing

    Circular Models for Consumer Staples

    CPI Works to Reduce Formulation Risks
    Contract Manufacturing / Private Label Directory
    Buyer's Guide
    Add New Company
    Corporate Profiles
    International Buyers Guide Companies
    Sabinsa Cosmetics, a division of Sabinsa Corporation

    Accupac

    CIE

    Ashland

    Croda
    Live From Shows
    Meetings
    Webinars
    Snapshots
    • Magazine
      • Current / Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Formulary
    • Directories
      • Buyer's Guide
      • Contract Manufacturing / Private Label Directory
      • Corporate Profiles
      • Add Your Company
    • Raw Materials
      • Actives
      • Functional Ingredients
      • Pigments
      • Polymers
      • Preservatives
      • Surfactants
    • End-User
      • Air Care/Environmental Fragrance
      • AP/Deo
      • Color Cosmetics
      • Disinfectants
      • Fine Fragrance
      • Hair Care
      • Household Cleaning
      • I&I Marketplace
      • Laundry Care
      • Oral Care
      • OTC/Medicated
      • Packaging
      • Personal Cleansers
      • Skin Care
      • Sun Care
      • Testing
    • Packaging
      • Lab Equipment
      • Mixing
      • Packaging
      • Testing
    • Top Companies
      • International Top 30 Report
      • Top 50 Report
    • Online Exclusives
    • Experts Opinion
    • Slideshows
    • Videos
    • Podcasts
    • eBook
    • Infographics
    • Blog
    • Whitepapers
    • Surveys
      • R & D Salary Survey
      • Sales & Marketing Salary Survey
    • Job Banks
    • Events
      • Industry Events
      • Live from show Events
      • Webinars
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Anti-aging & Cosmeceutical Corner

    Unexpected Anti-Aging Benefits From Alzheimer’s Treatment

    Alzheimer's Disease may hold key for anti-aging.

    Related CONTENT
    • Sharp Competition
    • A Review of Anti-Aging Device Technologies
    • Ingredients and Results in Anti-Aging
    • How Acids Enhance Anti-aging Products
    • Terminalia: An Ayurvedic Super Anti-Ager?
    Navin M. Geria01.04.16
    Alzheimer’s disease is the sixth-leading cause of death in the US and it is the only cause of death among the top 10 in the country that cannot be prevented, cured or even slowed, according to the Alzheimer’s Association. As the US and global populations continue to age, the rate of Alzheimer’s is expected to increase around the world. No wonder why researchers are scrambling to understand this dreaded disease. Now, an experimental drug treatment for Alzheimer’s disease has also demonstrated a host of unexpected anti-aging benefits in animals. This column will briefly review this exciting new development.


    Alzheimer’s disease afflicts more than five million Americans. It is also the most common cause of dementia in older adults, according to the National Institute of Health.


    According to an article published in the Nov. 12, 2015 issue of the Journal of Aging, Salk Institute for Biological Studies,  researchers Drs. Antonio Currais and David Shubert discovered unanticipated anti-aging benefits after treating laboratory mice with an experimental drug dubbed, J-147. The drug worked well in a mouse model of aging not typically used in Alzheimer’s research. The research team’s goal was to explore the effects of this drug on a particular breed of mice that has specific characteristics of aging rapidly and simultaneously experiencing a version of dementia that more closely resembles the age-related human disorder.


    Improved Gene Expression


    Mice that received J-147 performed better on memory and other tests for cognition and also displayed more robust motor movements, according to researchers, who focused on old age itself (a major risk factor for this disease), instead of the usual route of detecting amyloid plaque deposits in the brain.


    Remarkably, the treated mice showed fewer pathological signs of Alzheimer’s in their brains. Furthermore, many aspects of gene expression were very similar to those of young animals. These included markers of increased metabolism, healthier brain blood vessels, better memory and cognition, reduced inflammation and levels of oxidized fatty acids. It also prevented in the brain, blood leakage from the micro-vessels, while also improving other physiological features. Damaged blood vessels are a common feature of aging in general, and in Alzheimer’s in particular.


    The researchers said that they did not predict the anti-aging effect; where J-147 made old mice act younger; with improved physiology, memory and an appearance that more closely resembled young mice.


    Although these studies represent a new and exciting approach to Alzheimer’s drug discovery via animal testing in the context of aging, the researchers said that the only way to demonstrate the clinical relevance of the work is to proceed to human clinical trials, which are slated to begin next year, with auxiliary anti-aging benefits. This research demonstrates that such scientifically-proven interventions can improve our aging profile.


    Furthermore, recent scientific studies have shown that proper nutrition can stimulate systems in the body that have been slowed by the aging process, and restore more youthful functionality. It is important to realize that the rate at which we age is under more of our control than was once thought to be possible.


    Navin M. Geria
    Senior Technical Advisor  and Principal Doctors Skin Prescription
    tokuho02@gmail.com 

    Navin Geria, ex-Pfizer Research Fellow, is senior technical advisor and principal of the dermatological research company, Doctors Skin Prescription (DSP), Boston, founded by dermatologist David J. Goldberg, MD JD and plastic surgeons William P. Adams, MD FACS and Jason Pozner, MD. Geria has more than 30 years of experience in the personal care industry and was previously with Clairol, Warner-Lambert, Schick, Bristol-Myers and most recently, Spa Dermaceuticals. He has earned nearly 20 US patents, has been published extensively and has been both a speaker and a moderator at cosmetic industry events. www.dspskincare.com
    Related Searches
    • care
    • global
    • industry
    • spa
    Related Knowledge Center
    • Functional Ingredients
    • Skin Care
    • Testing
    Suggested For You
    Anti-Aging and Ayurveda are part of well-being Anti-Aging and Ayurveda are part of well-being
    There Will Be Blood There Will Be Blood
    Dermaflash and Perricone Create Kit Dermaflash and Perricone Create Kit
    Skin Care Sensation Skin Care Sensation
    Anti-Aging Efficacy Of Topical Green Tea Products Anti-Aging Efficacy Of Topical Green Tea Products
    The Science of Ceramides Improves Aging Skin The Science of Ceramides Improves Aging Skin
    Skin Lightening Properties of Ascorbic Acid Skin Lightening Properties of Ascorbic Acid
    Filmexel Debuts from Silab Filmexel Debuts from Silab
    Terminalia: An Ayurvedic Super Anti-Ager? Terminalia: An Ayurvedic Super Anti-Ager?
    How Acids Enhance Anti-aging Products How Acids Enhance Anti-aging Products
    Ingredients and Results in Anti-Aging Ingredients and Results in Anti-Aging
    A Review of Anti-Aging Device Technologies A Review of Anti-Aging Device Technologies
    Sharp Competition Sharp Competition

    Related Anti-aging & Cosmeceutical Corner

    • Actives | Functional Ingredients | OTC/Medicated | Skin Care

      Understanding the Barrier & Keeping It Healthy

      The stratum corneum (SC) consists of corneocytes and intercellular lipids such as ceramides (40%), cholesterol (25%) and free fatty acids (10%). This lipid mixture is vital to maintaining barrier integrity. The SC is also known as the permeability ba…
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 11.01.19

    • Actives | Skin Care
      Delivering Wellness Via a Variety of Channels

      Delivering Wellness Via a Variety of Channels

      The consumer’s mindset is shifting, accepting “aging” as a part of life; they embrace the passing of time and focus on wellness and want cosmetic solutions to support wellness. This shift coincides with the emerging quest for wellbe…
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 09.02.19

    • Functional Ingredients | Skin Care

      If It Works for Tigers It’ll Work for You!

      Cica creams are anti-aging moisturizers that get their name from one of the main ingredients in the formulation, Centella asiatica (aka cica), which helps repair the skin barrier to resist visible signs of aging. According to tradition, wounded tiger…
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 07.01.19


    • Actives | Skin Care

      Cosmeceutical Trends Worth Watching

      According to dermatologists Zoe Draelos, MD and Ranella Hirsch, MD, seven of the most popular cosmeceutical categories are: moisturizers, retinoids, exfoliants, anti-inflammatories, antioxidants, barrier repair and stem cells. In Q1 2018, US prestige…
      Navin M. Geria, AyurDerm Technologies, LLC 03.04.19

    • Actives | Functional Ingredients | Skin Care

      Several Very Big Beauty Benefits Are Derived from Micronutrients

      From a relatively small base, the cosmetics antioxidant market is growing more slowly than the global beauty supplement market as a whole. According to Marketandmarkets.com, the cosmetics antioxidant market is projected to grow from $109.0 million in…
      Navin M. Geria, AyurDerm Technologies, LLC 09.03.18

    • Actives | Functional Ingredients | Skin Care

      Health Benefits of MitoQ Antioxidant Technology

      Many health conscious consumers understand the value of antioxidant supplements and topicals. Allied Market Research has estimated the global antioxidants market generated $2.92 billion in 2015 and predicted it would reach $4.53 billion by 2022, regi…
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 07.02.18


    • Actives | Skin Care

      Formulation and Efficacy of Anti-Aging Moisturizers

      According to IRI data, mass market sales of skin care products rose 2.1%, but sales of facial anti-aging products dropped 3.5% to $1.04 billion. After posting 8% growth for several years in the past decade, facial skin care sales slowed to just 1% gr…
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 05.01.18

    • Actives | Skin Care

      Understanding How Collagen Helps Healthy Looking Skin

      Global sales of collagen products are expected to reach $9.3 billion by 2023 and the market for nutricosmetics will be worth $7.4 billion by 2020 driven, in part, by an aging population and a growing acceptance of functional foods, according to a rep…
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 01.04.18

    • Actives | Skin Care

      Questions Arise Over Plant Stem Cells

      Stem cells are found in both plants and animals. They divide and can differentiate into a range of cell types. It is this regenerative property of plant stem cells that has captured the imagination of cosmetic researchers. In this column, we will bri…
      Navin M. Geria, AyurDerm Technologies, LLC 09.01.17


    • Actives | Skin Care
      Probiotics Play a Key Role In Maintaining Skin Health

      Probiotics Play a Key Role In Maintaining Skin Health

      An inside out approach to skin care.
      Navin M. Geria, AyurDerm Technologies, LLC 07.03.17

    • Functional Ingredients | Skin Care

      Anti-Aging and Ayurveda are part of well-being

      Ayurveda is fast-becoming a preferred lifestyle option around the world, and it is poised for a quantum leap today as Western companies realize its potential and Western consumers realize its benefits. Ayurveda is the age-old science of well-being, w…
      Navin M. Geria, AyurDerm Technologies, LLC 05.01.17

    • Actives | Functional Ingredients | Preservatives | Skin Care | Testing
      There Will Be Blood

      There Will Be Blood

      A new idea in anti-aging.
      Navin M. Geria, AyurDerm Technologies, LLC 02.27.17

    • Actives | Skin Care

      MIT Adds a New Wrinkle To Anti-Aging Technology

      Consumers go to great lengths to reduce the appearance of wrinkles. MIT researchers took a very scientific approach to this problem and created a cream with impressive anti-wrinkle results. This column will briefly review the chemistry and benefits o…
      Navin Geria, AyurDerm Technologies 01.06.17

    • Actives | Functional Ingredients | Skin Care

      Anti-Aging Efficacy Of Topical Green Tea Products

      Consumers prefer cosmetic formulas that are promoted for their antioxidant properties, according to Packaged Facts, a market research company. In recent years, retail sales of these products exceeded $4 billion, with skin care products accounting for…
      Navin M. Geria, Ayurderm Technologies LLC 11.02.16

    • OTC/Medicated | Skin Care

      The Science of Ceramides Improves Aging Skin

      Ceramides are the major component of the skin’s surface. They protect against moisture loss to keep skin youthful, supple and nourish the skin from within. In this column, we will briefly review the science of ceramides and how they improve agi…
      Navin M. Geria, Geria Skin Care 09.01.16

    Breaking News
    • Birchbox Partners with Buzzfeed
    • Coty Strengthens Its Leadership
    • Jennifer Garner Joins Virtue Labs
    • Perfect Corp. Partners with Sally Beauty
    • Dollar General To Sell CBD Beauty
    View Breaking News >
    CURRENT ISSUE

    December 2019

    • In Sickness & in Health
    • In Action
    • Tress Test
    • From Hollywood to Hair Color
    • Virtual Reality for Makeup Is Not Make Believe
    • Members of the Club
    • A New Era in Efficacy Testing
    • View More >
    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    Deerland Obtains Certification from Australia’s Therapeutic Goods Administration
    OptiMSM Shown to Improve Hair & Nail Appearance and Condition
    DCC Acquires Contract Manufacturer Ion Laboratories
    Coatings World

    Latest Breaking News From Coatings World

    Beckers Group Announces Global Price Increase on Coil, Industrial Coatings
    Evonik, Wynca Celebrate Groundbreaking of New Fumed Silica Plant in Zhenjiang
    Personnel Changes in Corporate Communications, Government Relations at BASF
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    15-Year Tele-Critical Care Collabration Yields Significant ICU Improvement Results
    Prellis Biologics' New Tool Simplifies Complex Tissue Engineering
    InspireMD's CEO Steps Down
    Contract Pharma

    Latest Breaking News From Contract Pharma

    CatSci Expands Capabilities with Lab Expansion
    Smart Tags on Pills Set to Improve Supply Chain Security and Patient Adherence
    PCI Pharma Services Invests in Tredegar, UK Site
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Time Features 5 Best Beauty Inventions
    CES 2020 Preview - Innovation Award Honorees in Health & Wellness
    Star of E!'s Botched Gets Line Leaping Bunny Certified
    Happi

    Latest Breaking News From Happi

    Birchbox Partners with Buzzfeed
    Coty Strengthens Its Leadership
    Jennifer Garner Joins Virtue Labs
    Ink World

    Latest Breaking News From Ink World

    Smurfit Kappa, Wings for Aid Create Disaster Relief Packaging Solution
    ePac Flexible Packaging Expands into Asia Pacific Market
    United Carton Industries Company Invests in EFI Nozomi Corrugated Printer
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    Luminer promotes Heather Bookman to prepress manager
    Materials Exchange launches to solve excess inventory issue
    Mark Andy joins forces with UPM Raflatac
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Simavita Set to License Sensor Technology in EU
    NDC Appoints President
    AATC Adds Two Scholarships
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    TriMed Closes Out FDA Warning Letter
    FDA OKs Shoulder Innovations' Augmented Glenoids for Total Shoulder System
    OrthoGrid Systems Receives FDA 510(k) Clearance for New PhantomMSK Trauma Application
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    SEMI Releases Global Semiconductor Equipment Sales Forecast
    eMagin Corporation Announces Approximately $4.3 Million Order for Military Program
    CPI Supports Smart Food-labeling Project Set to Reduce Food Waste in 2020

    Copyright © 2019 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.