01.04.18
US Patent No. 9,833,393 B2; ELC Management LLC, Melville, NY, has been awarded a patent for a method for increasing or synchronizing per1 gene expression in skin cells having decreased, irregular, or asynchronous per1 gene expression. The method is comprised of topically applying to skin cells a composition comprising an ingredient selected from the group consisting of Salvia hispanica (chia) extract, Prunus armeniaca (apricot) kernel oil and mixtures thereof, wherein the ingredient is characterized by causing an increase in per1 expression ranging from 9.1 to 64% when exposed to skin cells in vitro at a concentration within the range of 0.01 to 0.1%.