By Marilyn Barrett, PhD, Pharmacognosy Consulting, Inc., Mary Ellen Cosenza, PhD, MEC Regulatory & Toxicology Consulting, Steven Dentali, PhD, Dentali Botanical Sciences, and Sandy Bigelow, PhD, Vanguard Global Associates LLC04.10.20
Significant public interest and consumer acceptance of cannabidiol (CBD) over the last 2-3 years has created a burgeoning marketplace with estimated sales last year of $5 billion. It cannot be denied that products purporting to contain CBD are pervasive.
CBD is a terpenoid-phenolic compound, one of a class of compounds called cannabinoids that are produced in the resinous hairs (glandular trichomes) of Cannabis sativa L. The group of 20-plus major cannabinoids includes other cannabinoids such as Δ9-tetrahydrocannabinol (THC), its degradation product cannabinol, cannabigerol, cannabichromene and tetrahydrocannabivarin. THC produces psychogenic effects that may be associated with habitual use via regular cannabis smoking or ingestion of edibles. CBD has been found not to exert psychogenic effects and not to promote habitual use, thus exhibiting a limited potential for abuse.
Regulatory Matters
Until recently, all products made from cannabis were categorized as schedule I drugs, as per the Controlled Substances Act of 1970 (21 USC §801). Schedule I drugs are substances with no curren
CBD is a terpenoid-phenolic compound, one of a class of compounds called cannabinoids that are produced in the resinous hairs (glandular trichomes) of Cannabis sativa L. The group of 20-plus major cannabinoids includes other cannabinoids such as Δ9-tetrahydrocannabinol (THC), its degradation product cannabinol, cannabigerol, cannabichromene and tetrahydrocannabivarin. THC produces psychogenic effects that may be associated with habitual use via regular cannabis smoking or ingestion of edibles. CBD has been found not to exert psychogenic effects and not to promote habitual use, thus exhibiting a limited potential for abuse.
Regulatory Matters
Until recently, all products made from cannabis were categorized as schedule I drugs, as per the Controlled Substances Act of 1970 (21 USC §801). Schedule I drugs are substances with no curren
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