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Chemyunion Launches Revinage


A retinoid alternative at stand 1437.

Retinoids are among the most prescribed and recommended agents in dermatological therapy, but Chemyunion notes that these actives are associated with photosensitivity and skin irritation.

Chemyunion says new Revinage is an active composed of a botanical supercritical extract. This top-of-the-line green chemistry technology, which allows obtaining highly concentrated, solvent-free extracts, meets all requirements for an environmentally-sustainable product. Revinage is rich in phytol, a precursor of phytanic acid, that is a ligand of Retinoid X Receptor (RXR) as shown by Chemyunion's silico studies.

Revinage multi-targets skin aging. In vitro tests show its capacity to:
• Increase collagen synthesis by 24% and elastin by 26%;
• Increase the level of cell turnover factors EGF and TGF-beta by 108% and 41%, respectively;
• Increase antioxidant enzymes CAT and SOD by 47% and 247%, respectively; and
• Reduce inflammatory mediators COX-2, PGE2 and LTB4, by 69%, 26% and 28%, respectively.

According to Chemyunion, clinical trials also proved the effects of Revinage. After 42 days of treatment with Revinage, deep wrinkles were reduced by 28% and skin roughness by 36%. Elasticity and dermis redensification were also increased by 13% and 25%, respectively.

More info: Chemyunion, Email:; Website: