Efficacy Challenges


  • In Vitro, In Vivo, Ex Vivo; What Does It All Mean?

    Articles and advertisements in beauty magazines proclaim remarkable results for skin care treatments. Sometimes these claims are punctuated with an asterisk and, at the bottom of the page, the asterisk is associated with small-print-characters readin…
    Paolo Giacomoni, PhD, Insight Analysis Consulting 11.01.19

  • Actives | Functional Ingredients | Skin Care
    The Important Role of pH in Beauty Care Formulation

    The Important Role of pH in Beauty Care Formulation

    We use the word “acidic” in many instances: this wine is way too acidic, the soil of that field is not sufficiently acidic, her sarcastic remark was acidic in its conclusion, etc. Despite this loose use of the word acid, acidity is a well…
    Paolo Giacomoni, PhD, Insight Analysis Consulting 09.02.19

  • Actives | Skin Care

    Some Gut Feelings Regarding the Microbiome

    The body harbors trillions of microorganisms. In fact, they all add up to three to four pounds of biomaterial; which is to say, about the weight of our brain. Until recently, bacteria were identified by the nutrients necessary for their growth and mu…
    Paolo Giacomoni, PhD, Insight Analysis Consulting 01.01.19

  • Actives | Functional Ingredients | OTC/Medicated | Skin Care

    Thick to Thin, the Impact of Menopause on Skin

    Menopause can significantly affect a woman’s health but, whereas the psychological effects of menopause are often unfathomable, the cutaneous ones are well known. In anatomical regions exposed to environmental factors such as the forearm or the…
    Paolo Giacomoni, PhD, Insight Analysis Consulting 11.08.18

  • Efficacy Challenges

    Thick to Thin, the Impact Of Menopause on Skin
    Paolo Giacomoni, PhD, Insight Analysis Consulting 11.01.18

  • Thick to Thin, the Impact of Menopause on Skin

    Menopause can significantly affect a woman’s health but, whereas the psychological effects of menopause are often unfathomable, the cutaneous ones are well known. In anatomical regions exposed to environmental factors such as the forearm or the…
    Paolo Giacomoni, PhD , Insight Analysis Consulting 11.01.18

  • Actives | Skin Care

    Understanding the Wrinkle

    The single worst threat to beauty and self-image perceived by Caucasian women in the Western world is the wrinkle, according to several surveys conducted in recent years. In contrast, Asian women are more worried by discoloration and brown spots, whi…
    Paolo Giacomoni, PhD, Insight Analysis Consulting 09.06.18