Hypermarcas Patents Depigmenting Composition

US Patent No. 9,526,690 B2; Hypermarcas SA, São Paulo, has earned a patent for a method of preparing a depigmenting cosmetic composition. The method entails the following steps:

• Providing an aqueous phase, wherein a vehicle, a sequestrant, a tamponing ingredient, and a thickener are homogenized;
• Providing an oily phase comprising an antioxidizer, one or more emollients, and one or more emulsifiers, followed by addition of a first whitening agent to the oily phase and homogenization, wherein the first whitening agent is undecylenoyl phenylalanine;
• Adding the oily phase to the aqueous phase under vacuum, thereby forming an emulsion comprising an internal micelle phase and an external micelle phase, wherein homogenization is maintained, and wherein the first whitening agent is in the internal micelle phase;
• Adding a first solution comprising a second whitening agent solubilized in water to the emulsion formed in step C, wherein homogenization is maintained, wherein the second whitening agent is in the external micelle phase, and wherein the second whitening agent is alpha-arbutin, to form an emulsion with an internal and external micelle phase;
• Adding a second solution comprising a third whitening agent dissolved in glycerin to the emulsion formed in step D, wherein the third whitening agent is in the external micelle phase, and wherein the third whitening agent is kojic acid to form an emulsion with an internal and external micelle phase; and
• Adding an emollient followed by a fourth whitening agent to the emulsion formed in step E, followed by homogenization, thereby forming the depigmenting cosmetic composition, wherein the fourth whitening agent is in the external micelle phase, and wherein the fourth whitening agent is brassica napus extract.