Berkem Rolls Out New Actives

Berkem has applied its plant extraction expertise and omic sciences in order to screen and develop active extracts from three plants: bilberry, oregano and quince. Thereafter, in vitro efficacy tests have allowed to showcase specific mechanism of action, to each active.
 
Aqua’Protek, oregano extract, acts on epidermal keratinocytes leading to a significantly dose- dependent increase of loricrine rate, following an inflammatory stress (TNF-α). By inducing the increase of loricrine, Aqua’Protek protects the cornified envelope damaged due to an inflammatory stress. It helps to maintain impermeability and thus a state of skin hydration.
 
Chrono’Protek is a quince extract. Its action on dermal fibroblasts after an exposition to a UVA stress, shows a dose-dependent decrease in the quantity of MMP-1 produced by fibroblasts. Chrono’Protek protects the collagen pool of the extracellular matrix. Skin becomes firm and re-plumps.
 
Screen’Protek, bilberry extract, has shown an action on the barrier function of epidermal keratinocytes. Indeed, after the addition of the extract with an inflammatory stress (IL-17), the protection rate of the barrier function shows a dose-dependent increase. Screen’Protek restores the skin barrier deteriorated due to an inflammatory stress and acts as a shield against exterior assaults.
 
To use between 1 to 5% in formulation, those three extracts are recommended in protection care for skin and body.
 
More info: www.berkem.com