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In an open label, single arm study, objective measurements demonstrated improvement in cosmetic skin architecture.
September 16, 2022
By: Christine Esposito
Editor-in-Chief
Carlsbad, CA -based DefenAge Skincare has reported a new comprehensive clinical study of its 10 Luxe Hand & Body Cream with Age-Repair Defensins. Proprietary to DefenAge, defensin-molecules are capable of reactivating latent LGR6 stem cells in the basal layer of skin. When applied topically, these molecules can reduce visible signs of skin aging (including the loss of hydration and elasticity) and visibly increase skin thickness, concludes the peer-review article entitled “Impact of Defensins-Containing Body Cream on Skin Composition” and published by the Journal of Cosmetic Dermatology. The Journal of Cosmetic Dermatology study corroborates the high-performance of the multi-pillar formulation, which addresses all key areas of caring for body skin, including global anti-aging via defensin-molecules, repairing the skin moisturization barrier and hydration, and reducing inflammation, said DefenAge Skincare. In this open label, single arm clinical study, subjects reported significant improvement across all subjective skin domains and objective measurements demonstrated improvement in cosmetic skin architecture, including visible improvement in elasticity, hydration, and appearance of skin thickness when the body cream was applied daily for six weeks. “Use of a Defensin-containing topical body cream resulted in the dramatic improvement in multiple skin qualities on challenging body areas including the hands, forearms, elbows, and knees,” said clinical investigator and principal author of the article Kristen Echanique, MD. “The stimulation of collagen and improvements seen in viscoelasticity and skin hydration were remarkable. Study participants also reported subjective improvements in dryness and discomfort, and in the appearance of the skin’s roughness, wrinkling, redness, age spots, and pigmentation.” The 10 Luxe Hand & Body Cream was recently named Best-in-Class Body in Good Housekeeping’s Beauty Awards.
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