Ginkgo Biloba, Eucalyptus Under CIR Review

At the 145th meeting of the Cosmetic Ingredient Review Expert Panel, held Dec. 4-5, 2017, final safety assessments and other news were unveiled. The meeting agenda includes the consideration of 14 ingredient groups advancing in the review process—including eight final reports, three tentative reports and three draft reports.


Also, following up on the panel’s continuing standardization of guidance language documents, the agenda contains three items regarding hair dyes. Here are the findings:

Final Safety Assessments

• Ammonia and Ammonium Hydroxide – 2 ingredients – Split conclusion (safe with qualifications in each)
• Persulfates – 3 ingredients – Split conclusion
• Polysilsesquioxanes – 18 ingredients – Safe as used
• Triglycerides – 51 ingredients – Safe as used
• Panthenol, Pantothenic Acid, and Derivatives – 7 ingredients – Safe as used

• Malic Acid and Sodium Malate – 2 ingredients – Safe as used
• Mentha piperita (Peppermint)-Derived Ingredients –
• 10 ingredients – Split conclusion
• Alkyl Sultaines – 13 ingredients – Safe as used
• Zinc Salts – 27 ingredients – Safe with non-irritating caveat
• Alkane Diols – 10 ingredients – Split conclusion
• Hamamelis virginiana (Witch Hazel)-Derived Ingredients – 8 ingredient – Safe with non-irritating and non-sensitizing caveats

• Ginkgo biloba-Derived Ingredients – 10 ingredients
• Eucalyptus globulus (Eucalyptus)-Derived Ingredients – 6 ingredients

• Polyaminopropyl Biguanide (polyhexamethylene biguanide hydrochloride) – 1 ingredient