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Exploring interaction between micro signaling molecule and skin activities.
June 4, 2020
By: Happi Staff
To further advance more than a decade of circadian rhythm research in skin, the Estée Lauder brand has inked a collaboration with Dr. Paolo Sassone-Corsi, director of the Center for Epigenetics and Metabolism at the University of California, Irvine. This research collaboration connects Estée Lauder's skin biology research program with the expertise and complementary research focus of Dr. Sassone-Corsi. This new collaboration will build upon Estée Lauder's skin research and contribute to its recent findings by investigating additional molecular mechanisms related to a newly identified micro signaling molecule. The two laboratories will independently explore the interaction between this molecule and other skin activities, including circadian machinery, to deepen the understanding of how skin acts and communicates. This research seeks new information about how this powerful micro signaling molecule interacts with essential skin pathways, in order to better understand how to impact the “memory” of skin to help it act and look younger. “We are excited to embark on a collaboration with Dr. Paolo Sassone-Corsi, who is a world leader in epigenetics research,” said Dr. Nadine Pernodet, vice president, skin biology and bioactives, R&D at the Estée Lauder Companies, and Estée Lauder lead scientist. “Dr. Sassone-Corsi has brought many firsts to the field of epigenetics and our laboratory has pioneered research in skin biology. This collaboration will allow us to explore the common interests of our two research groups and will help us further our understanding of what is happening in the skin.” “I'm very impressed with Estée Lauder's research and understanding of new ways to help change skin's visible future,” said Dr. Sassone-Corsi. “This exciting collaboration provides the opportunity to unravel how a specific micro signaling molecule interacts with circadian rhythms in the skin, a critical organ system that we wish to explore more in depth in my laboratory.” Over the past three decades, Dr. Paolo Sassone-Corsi has conducted research focused on unraveling how epigenetics is critical for healthy lifespan, wellbeing, appropriate circadian sleep cycles, aging and disease prevention. His seminal discoveries have changed the circadian clock paradigm, proving the existence of secondary clocks that control peripheral tissues throughout the body. Research conducted in the Sassone-Corsi Laboratory has charted new territory in understanding how circadian clocks communicate to synchronize cellular processes, linking epigenetics and metabolism in a vast array of biological systems. Dr. Sassone-Corsi has published several hundred peer-reviewed articles, many in the highest impact science journals, and has received an expansive list of prestigious international scientific awards.
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