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RIFM Study Looks at Fragrance Allergy

Much needed data for global public health.

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By: TOM BRANNA

Editor

The first article from the Research Institute for Fragrance Materials, Inc. (RIFM) sponsored, global study on the true prevalence of contact allergy to fragrances is now available from the RIFM website at www.rifm.org/publications-details.php?id=22. The article, Design and Feasibility of an International Study Assessing the Prevalence of Contact Allergy to Fragrances in the General Population: The European Dermato-Epidemiology Network Fragrance Study, Marta Rossi et al., was published in the peer-reviewed journal, Dermatology, in late 2010; 221:267-275. Printed copies are available by e-mailing [email protected].

Sponsored by RIFM, the global fragrance study is being conducted by the European Dermato-Epidemiology Network (EDEN). It is the first time that the true prevalence of contact allergy to fragrances in the general population is being measured on a global scale. RIFM initiated the study; The Expert Panel endorsed it and EDEN as a unique resource to conduct it. The EDEN Fragrance Study is conducted in collaboration with the European Society of Contact Dermatitis (ESCD) and coordinated by the Centro Studi GISED, Ospedali Riuniti di Bergamo. Though mainly supported by RIFM, additional support comes from The Netherlands Institute for Public Health and Environment, and the Foundation of Occupational and Environmental Dermatology. The ongoing study is reviewed by the Expert Panel.

The aim of this paper is to report on the methodology and reliability of instrumentation adopted by EDEN and to discuss the feasibility of the study based on the pilot phase that occurred from December 2006 to May 2007. The conclusion was that the global study is feasible and would provide useful and reliable data that would contribute to public health. The European phase of the global study has already been completed and the data is being analyzed. Plans are to start the North American phase in 2012.

This article also publishes the patch testing protocol used throughout the study. According to RIFM, it is the first time that a patch testing protocol, application and reading, was standardized across multiple testing centers in a region. This protocol can now be used as a gold standard for testing contact allergy not only to fragrances but any sensitizer.

More info: www.rifm.org or e-mail [email protected].

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