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Seiwa Kasei Presents New Data on Vitamin C Derivative Amitose DGA

Company conducted a STE (short time exposure) test.

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By: Lianna Albrizio

Associate Editor

Amitose DGA (Bis-Glyceryl Ascorbate) is Seiwa Kasei’s original patented vitamin C derivative and high-stability and moisturizing are important. Oftentimes, there is low stimulation compared with other vitamin C derivatives.
 
Seiwa Kasei performed a short time exposure test (STE) with Amitose DGA and some of vitamin C. The test is an in-vitro test to check the stimulation of material. SIRC cells are cultivated containing vitamin C, and the survival rate (viability) are checked a few hours later. 
 
The results found that there is not a substantial difference between each vitamin C derivative at 0.05% of lower dosage. However, the survival rate for Amitose DGA was much higher than Sodium Ascorbyl Phosphate and 3-O-Ethyl Ascorbic Acid at 5% of high dosage.   
 
For formulators wanting to use a high dosage of vitamin C, Seiwa Kasei recommends Amitose DGA in terms of safety. 
 

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