• Login
    • Join
  • Subscribe Free
    • Magazine
    • eNewsletter
    Checkout
    • Magazine
    • News
    • Formulary
    • Exclusives
    • Top Companies
    • Raw Materials
    • End-User
    • Packaging
    • Directories
    • Events
    • Jobs
    • More
  • Magazine
  • News
  • Formulary
  • Exclusives
  • Top Companies
  • Raw Materials
  • End-User
  • Packaging
  • Directories
  • Events
  • Jobs
  • Current / Back Issues
    Features
    Columns
    Editorial
    Digital Edition
    eNewsletter Archive
    Our Team
    Editorial Guidelines
    Subscribe Now
    Advertise Now
    Top Features
    A Conversation with the Responsible Flushing Alliance

    Nice-Pak Meets Consumer Demands

    Wipes Manufacturers Meet Demand Surge

    Home Care Wipes: Sustainability in Sharper Focus as Cleaning Frenzy Simmers Following Pandemic

    Formulating with Alternatives In Personal Care Products
    Online Exclusives
    Association News
    Breaking News
    Financial News
    Industry News
    International
    Marketing News
    New Products
    News Front
    Packaging News
    Patents
    Personnel
    Regulations
    Snapshots
    Top News
    Live From Shows
    Top News
    P&G Emphasizes Small Actions at Home To Be More Sustainable

    L'Oréal's Sales Jump on Gains in China and E-Commerce

    PCPC Virtual Summit Features Legal & Regulatory Conference

    Biolage Unveils ColorBalm Hair Conditioners With Hair Color Benefits

    HCPA Opens Registration for New Horizons Cleaning Industry Conference
    Blog
    Online Exclusives
    Infographics
    Podcasts
    Whitepapers
    Videos
    Expert's Opinion
    HappiTV
    eBook
    Surveys
    International Top 30 Report
    Top 50 Report
    Top Companies
    8. LVMH

    17. Revlon

    4. SC Johnson

    50. Herbalife

    15. Sun Products
    Actives
    Functional Ingredients
    Pigments
    Polymers
    Preservatives
    Surfactants

    L'Oréal's Sales Jump on Gains in China and E-Commerce

    Reckitt Seeks Germ-Killing Innovations

    Mariano Puig Planas Dies at 93

    Videobite: Innospec's Answer to the 1,4-Dioxane Problem

    BASF Increases Price of Kaolin
    Air Care/Environmental Fragrance
    AP/Deo
    Color Cosmetics
    Disinfectants
    Fine Fragrance
    Hair Care
    Household Cleaning
    I&I Marketplace
    Laundry Care
    Oral Care
    OTC/Medicated
    Packaging
    Personal Cleansers
    Skin Care
    Sun Care
    Testing

    P&G Emphasizes Small Actions at Home To Be More Sustainable

    L'Oréal's Sales Jump on Gains in China and E-Commerce

    Reckitt Seeks Germ-Killing Innovations

    PCPC Virtual Summit Features Legal & Regulatory Conference

    Biolage Unveils ColorBalm Hair Conditioners With Hair Color Benefits
    Lab Equipment
    Mixing
    Packaging
    Testing

    Admix Appoints COO to Advance Manufacturing, Supply Chain & Regulatory Compliance

    Tesco Eliminates Plastic Bags from Online Orders

    Hourglass To Launch Sustainable Cosmetics Line

    Carbon Data for Personal Care Labels

    L’Oréal Hong Kong Launches Cross-Brand Recycling Program
    Contract Manufacturing / Private Label Directory
    Buyer's Guide
    Add New Company
    Corporate Profiles
    International Buyers Guide Companies
    Ashland

    Praan Naturals

    Baralan USA

    Centerchem Inc

    LipoTrue Inc.
    Live From Shows
    Meetings
    Webinars
    Snapshots
    • Magazine
      • Current / Back Issues
      • Features
      • Editorial
      • Columns
      • Digital Edition
      • eNewsletter Archive
      • Subscribe Now
      • Advertise Now
    • Breaking News
    • Formulary
    • Directories
      • Buyer's Guide
      • Contract Manufacturing / Private Label Directory
      • Corporate Profiles
      • Add Your Company
    • Raw Materials
      • Actives
      • Functional Ingredients
      • Pigments
      • Polymers
      • Preservatives
      • Surfactants
    • End-User
      • Air Care/Environmental Fragrance
      • AP/Deo
      • Color Cosmetics
      • Disinfectants
      • Fine Fragrance
      • Hair Care
      • Household Cleaning
      • I&I Marketplace
      • Laundry Care
      • Oral Care
      • OTC/Medicated
      • Packaging
      • Personal Cleansers
      • Skin Care
      • Sun Care
      • Testing
    • Packaging
      • Lab Equipment
      • Mixing
      • Packaging
      • Testing
    • Top Companies
      • International Top 30 Report
      • Top 50 Report
    • Online Exclusives
    • Experts Opinion
    • Slideshows
    • HappiTV
    • Videos
    • Podcasts
    • eBook
    • Infographics
    • Blog
    • Whitepapers
    • Surveys
      • R & D Salary Survey
      • Sales & Marketing Salary Survey
    • Job Banks
    • Events
      • Industry Events
      • Live from show Events
      • Webinars
    • About Us
      • About Us
      • Contact Us
      • Advertise With Us
      • Privacy Policy
      • Terms of Use
    Anti-aging & Cosmeceutical Corner

    The Science of Ceramides Improves Aging Skin

    ...

    Related CONTENT
    • Isosorbide Di-(Linoleate/Oleate) Treats Xerotic Pruritic Skin
    • Eraclea Debuts Skin Care Range
    • Skin Care Actives During Inactivity
    • Register Now for Happi's Anti-Aging Conference & Exhibition
    • Skin Brightening, Lightening and Bleaching
    Navin M. Geria, Geria Skin Care09.01.16
    Ceramides are the major component of the skin’s surface. They protect against moisture loss to keep skin youthful, supple and nourish the skin from within. In this column, we will briefly review the science of ceramides and how they improve aging skin.


    In 2014, global sales of ceramides approached $240 million, a figure that is expected to exceed $360 million by 2022, for a CAGR of 5.2%, according to Grand View Market Research. This category is expected to post significant growth during the forecast period, due to changing lifestyles, skin aging problems, and more women entering the workforce, among other factors.


    There are nine types of ceramides in the stratum corneum, conveniently named ceramide 1 through ceramide 9, and they account for 40 to 50% of the lipids in this outermost layer.


    Ceramides serve as the glue that locks together the surface area of skin cells. They are produced in the granular layer of the epidermis below the stratum corneum. The stratum corneum generates enzymes, which convert phospholipids and other lipids into a mixture of ceramides, cholesterol and free fatty acids. They are waxy lipids found in the outer layer of skin cells that help regulate the water barrier and water-holding capacity in the skin by creating a water-impermeable protective organ to prevent excessive water loss as well as build a barrier against the entry of microorganisms.


    Unfortunately, ceramide levels decline as we get older; as a result, upper layers of the skin become noticeably become thinner and develop fine lines. Decreased ceramide levels are also associated with dry skin conditions such as atopic dermatitis, eczema and psoriasis. The good news is that by replenishing lost ceramides, skin is able to fortify itself and retain optimal moisture for a firmer, smoother look. Bi-layer forming lipids such as ceramides would impart the most optimum dry skin relief.


    Ceramides play an important part in cellular signaling such as regulatory differentiation, proliferation and programmed cell death. It is the main component of the stratum corneum of the epidermis. There are three types of lipids in stratum corneum; ceramides, fatty acids and cholesterol. These are lipids that spontaneously arrange in multiple bi-layers between and around the corneocytes. They create a resistant barrier to water. There has been a lot of research done to find methods to enhance the delivery of actives through the stratum corneum and as a result, many penetration enhancers have been developed for this purpose. There is some debate about how effective topical delivery system of ceramides. This is because it is very difficult for ceramides to travel through the layers of the skin. However, research indicates that substances can travel through hair follicles and pores, reach the growing levels of skin and improve the health of skin cells.


    Improving Penetration

    Ceramides are expensive ingredients and are usually found in higher-end skin care lines. But natural ceramides are very unstable substances and very costly to obtain, so synthetic ceramides are frequently used. Unfortunately, synthetic ceramides do not penetrate the skin as well as natural ceramides. Ceramide penetration improves substantially if the ceramides are integrated in liposomes.


    There are basically four stratum corneum-modifying cosmeceuticals: ceramides, cholesterol, urea and lactic acid. Ceramides are important to skin because they are an essential part of the lipid barrier. Most companies claim that applying ceramides to the skin or taking ceramides orally can, generally speaking, hydrate dry skin, renew, repair and firm aging skin and fill in lines and wrinkles. However, there are not enough clinical studies supporting these claims. Still, many companies are touting the benefits of ceramides.


    Since 1990, Elizabeth Arden has marketed a variety of expensive ceramide products as “anti-aging.” Kao claims that its ceramide-based Curel products replenish and repair skin by forming a protective barrier. CeraVe claims its ceramide-based product helps repair, replenish and protect the skin barrier to leave skin looking and feeling soft, clean and healthy.


    Manufacturers of phytoceramide pills claim that their products go from the gut into the bloodstream and then to the skin to penetrate it from the inner cells to the outer stratum corneum. Via this route, it is claimed that ceramides can reach the skin’s lower cells and upper layers to support elastin and collagen production to keep skin firm, perform their role in renewing skin cells from the inside out and integrate between the cells of the stratum corneum to keep the skin hydrated.


    The long-time use of ceramides in Japan and their safety data played a part in their approval by the US FDA. Clinical studies have shown promising benefits of ceramides in treating atopic dermatitis. There are few clinical studies, however, that clearly prove the benefits of either topical ceramides or oral phytoceramides in normal and aging skin.


    Ceramides are derived either from animal sources, such as cows or they are mostly extracted from sweet potatoes, whole-grains such as wheat, and brown rice. Wheat derived ceramides are used in many popular beauty drinks and nutritional supplements. It is helpful to know how ceramide appear on labels. It appears as ceramide PC-102 (Hydroxypropyl bislauramide MEA), ceramide PC-104, ceramide PC-108, ceramide 1, 2, 3, 111, 6-11, etc.


    Long-Term Benefits

    Ceramides are natural components of human skin. No one can dispute that many Asians look younger than their age; which is due, in part, to a rice-rich diet. This may be a contributor, because of the effects of eating natural phytoceramides contained in the rice. No wonder ceramides provide skin benefits from oral supplements and topical application. There is extensive medical evidence supporting their potential for promoting the development of healthy skin cells.


    Overall, skin care products containing ceramides appear to be safe and effective, but more clinical studies are needed to prove the benefits as claimed.


    Navin M. Geria
    Chief Scientific Officer
    AyurDerm Technologies, LLC
    navin@AyurDerm.com

    Navin Geria, former Pfizer Research Fellow is a cosmetic and pharmaceutical product development chemist and the chief scientific officer of AyurDerm Technologies LLC, which provides Ayurvedic, natural and cosmeceutical custom formulation development and consulting services to the spa-wellness-dermatology industries. He has launched dozens of cosmeceutical and ayurvedic anti-aging products. Geria has more than 30 years of experience in the personal care industry and was previously with Clairol, Warner-Lambert, Schick-Energizer, Bristol-Myers and Spa Dermaceuticals. He has nearly 20 US patents and has been published extensively. Geria edited the “Handbook of Skin-Aging Theories for Cosmetic Formulation Development” focus book published in April 2016 by Harry’s Cosmeticology. He is a speaker, moderator and chairman at cosmetic industry events.
    Related Searches
    • OTC/Medicated
    • Skin Care
    Related Knowledge Center
    • OTC/Medicated
    • Skin Care
    Suggested For You
    Isosorbide Di-(Linoleate/Oleate) Treats Xerotic Pruritic Skin Isosorbide Di-(Linoleate/Oleate) Treats Xerotic Pruritic Skin
    Eraclea Debuts Skin Care Range Eraclea Debuts Skin Care Range
    Skin Care Actives  During  Inactivity Skin Care Actives During Inactivity
    Register Now for Happi Register Now for Happi's Anti-Aging Conference & Exhibition
    Skin Brightening, Lightening and Bleaching Skin Brightening, Lightening and Bleaching
    In Defense of Sunscreen In Defense of Sunscreen
    Scorching Growth for Sun Care? Scorching Growth for Sun Care?
    Anti-Aging and Ayurveda are part of well-being Anti-Aging and Ayurveda are part of well-being
    ICCR-11 Session Set for May 25 ICCR-11 Session Set for May 25
    Morre-Tec Celebrates  30th Anniversary Morre-Tec Celebrates 30th Anniversary
    There Will Be Blood There Will Be Blood
    L L'Oréal To Acquire CeraVe
    CeraVe Creates ‘National Winter Skin Relief Day’ CeraVe Creates ‘National Winter Skin Relief Day’
    Anti-Aging Efficacy Of Topical Green Tea Products Anti-Aging Efficacy Of Topical Green Tea Products
    Unite Adds New Lazer Straight  And Boosta Products Unite Adds New Lazer Straight And Boosta Products

    Related Anti-aging & Cosmeceutical Corner

    • Actives | Skin Care
      Pandemic-Related Stress & Its Impact on Skin

      Pandemic-Related Stress & Its Impact on Skin

      ...
      Navin Geria, Ayurderm Technologies, LLC 03.02.21

    • Skin Care
      Breakthrough Oxygen Therapy Reverses the Aging Process

      Breakthrough Oxygen Therapy Reverses the Aging Process

      ...
      Navin Geria, Ayurderm Technologies, LLC 01.06.21

    • Actives | Skin Care
      Blue Light Defenses & Protective Skin Care

      Blue Light Defenses & Protective Skin Care

      ...
      Navin M. Geria, AyurDerm Technologies, LLC 11.05.20


    • Color Cosmetics | Functional Ingredients | Hair Care | Skin Care

      A Growing Glut of Gluten-Free

      Beauty launches are most prominent in the skin care, color cosmetics and hair care categories.
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 09.03.20

    • Functional Ingredients | Skin Care
      The Beauty Benefits of Anti-Aging Facial Oils

      The Beauty Benefits of Anti-Aging Facial Oils

      ...
      Navin M. Geria, AyurDerm Technologies, LLC 01.03.20

    • Actives | Functional Ingredients | OTC/Medicated | Skin Care

      Understanding the Barrier & Keeping It Healthy

      ...
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 11.01.19


    • Actives | Skin Care
      Delivering Wellness Via a Variety of Channels

      Delivering Wellness Via a Variety of Channels

      ...
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 09.02.19

    • Functional Ingredients | Skin Care

      If It Works for Tigers It’ll Work for You!

      ...
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 07.01.19

    • Actives | Skin Care

      Cosmeceutical Trends Worth Watching

      ...
      Navin M. Geria, AyurDerm Technologies, LLC 03.04.19


    • Actives | Functional Ingredients | Skin Care

      Several Very Big Beauty Benefits Are Derived from Micronutrients

      ...
      Navin M. Geria, AyurDerm Technologies, LLC 09.03.18

    • Actives | Functional Ingredients | Skin Care

      Health Benefits of MitoQ Antioxidant Technology

      ...
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 07.02.18

    • Actives | Skin Care

      Formulation and Efficacy of Anti-Aging Moisturizers

      ...
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 05.01.18


    • Actives | Skin Care

      Understanding How Collagen Helps Healthy Looking Skin

      ...
      Navin M. Geria, Chief Scientific Officer AyurDerm Technologies, LLC 01.04.18

    • Actives | Skin Care

      Questions Arise Over Plant Stem Cells

      ...
      Navin M. Geria, AyurDerm Technologies, LLC 09.01.17

    • Actives | Skin Care
      Probiotics Play a Key Role In Maintaining Skin Health

      Probiotics Play a Key Role In Maintaining Skin Health

      An inside out approach to skin care.
      Navin M. Geria, AyurDerm Technologies, LLC 07.03.17

    Trending
    • Sunscreen On The Spot
    • BASF Increases Price Of Kaolin
    • Henkel Appoints New EVP Of Beauty Care
    • Neutrogena Takes Action On Skin Health Disparities
    • Top Trending Skin Care Products Of 2021
    Breaking News
    • P&G Emphasizes Small Actions at Home To Be More Sustainable
    • L'Oréal's Sales Jump on Gains in China and E-Commerce
    • PCPC Virtual Summit Features Legal & Regulatory Conference
    • Biolage Unveils ColorBalm Hair Conditioners With Hair Color Benefits
    • New Synthetic Biology Coalition Formed in US
    View Breaking News >
    CURRENT ISSUE

    Household & Personal Care Wipes Spring 2021

    • A Conversation with the Responsible Flushing Alliance
    • Nice-Pak Meets Consumer Demands
    • Wipes Manufacturers Meet Demand Surge
    • Home Care Wipes: Sustainability in Sharper Focus as Cleaning Frenzy Simmers Following Pandemic
    • View More >

    Cookies help us to provide you with an excellent service. By using our website, you declare yourself in agreement with our use of cookies.
    You can obtain detailed information about the use of cookies on our website by clicking on "More information”.

    • About Us
    • Privacy Policy
    • Terms And Conditions
    • Contact Us

    follow us

    Subscribe
    Nutraceuticals World

    Latest Breaking News From Nutraceuticals World

    AstaReal Astaxanthin Ingredient Receives U.S. Patent Approval
    Study on Kemin’s DailyZz Botanical Blend Uncovers Sleep Quality, Next-Day Performance Benefits
    FDA’s Dr. Cara Welch Opening Speaker at the 9th AHPA Botanical Congress
    Coatings World

    Latest Breaking News From Coatings World

    Jebsen & Jessen, Innospec Sign Distribution Agreement
    IGL Coatings Announces Partnership in Finland
    Axalta Schedules 1Q 2021 Earnings Conference Call
    Medical Product Outsourcing

    Latest Breaking News From Medical Product Outsourcing

    Iterative Scopes Announces IBD-Focused Scientific Advisory Board
    Vicarious Surgical, D8 Holdings Corp. Combine Operations in $1.1 Billion Deal
    FDA Grants De Novo Clearance to Medtronic’s GI Genius Model
    Contract Pharma

    Latest Breaking News From Contract Pharma

    Bristol Myers Squibb Expands at Cambridge Crossing
    Amgen Completes Five Prime Acquisition
    Sartorius Expands in the UK
    Beauty Packaging

    Latest Breaking News From Beauty Packaging

    Lancôme Reveals New Global Sustainability Program
    First-Ever Skincare Line Focuses on Iron To Prevent Aging
    L’Oréal Reports Jump in Sales for First Quarter of 2021
    Happi

    Latest Breaking News From Happi

    P&G Emphasizes Small Actions at Home To Be More Sustainable
    L'Oréal's Sales Jump on Gains in China and E-Commerce
    PCPC Virtual Summit Features Legal & Regulatory Conference
    Ink World

    Latest Breaking News From Ink World

    Kumon North America Adds Speedmaster XL 106 from Heidelberg
    SE-DA Invests in Kornit Presto S
    Acrylic Resins Market Worth $21.9 Billion by 2025: MarketsandMarkets
    Label & Narrow Web

    Latest Breaking News From Label & Narrow Web

    TLMI reveals Eugene Singer Award winners at Virtual Spring Summit
    Monadnock Paper Mills joins SGP
    ACTEGA helps converter reach sustainability goals
    Nonwovens Industry

    Latest Breaking News From Nonwovens Industry

    Albaad to Add Natural-Based Line in Israel
    First Quality to Discontinue Tampon Operations
    Jessup Installs New Era Coating and Laminating Line
    Orthopedic Design & Technology

    Latest Breaking News From Orthopedic Design & Technology

    BioMagnetic Sciences Names President and CEO
    Mainstay Medical Launches ReActiv8 in Australia
    Biogennix Rolls Out Agilon Strip Bone Graft
    Printed Electronics Now

    Latest Breaking News From Printed Electronics Now

    Virtual ASMC 2021 Spotlights Advanced Semiconductor Manufacturing Excellence
    LG Display Cuts Down CO2-eq Emissions by 3 Million Tons in 2020
    European Commission's Innovation Radar Acknowledges 3 ARMOR Innovations

    Copyright © 2021 Rodman Media. All rights reserved. Use of this constitutes acceptance of our privacy policy The material on this site may not be reproduced, distributed, transmitted, or otherwise used, except with the prior written permission of Rodman Media.

    AD BLOCKER DETECTED

    Our website is made possible by displaying online advertisements to our visitors.
    Please consider supporting us by disabling your ad blocker.


    FREE SUBSCRIPTION Already a subscriber? Login