Hyaluronic Acid was first discovered in 1934 by two chemists from Columbia University. Karl Meyer and John Palmer isolated an extremely high molecular weight polysaccharide found in the vitreous of bovine eyes[1]. In 1979, Endre Balazs filed a patent[2] for ultrapure Hyaluronic Acid, which marked the commercialization of Hyaluronic Acid (HA) on an industrial scale.[3] Nowadays, industrial production of HA is mainly classified into two types: extraction from animal tissues and microbial fermentation.
Since its first discovery, research and studies on HA have shown a wide range of pharmaceutical and medical applications. For example, medical-grade HA was initially used for vitreous replacement during eye surgery. HA has also been found to be an excellent material in tissue engineering with applications in dermal fillers and osteoarthritis treatment.[4] Recent studies have also shown skin and joint benefits from ingesting HA through food and supplements.[5],[6]
Hyaluronic Acid skin benefits
Hyaluronic Acid, also known as hyaluronan, is a naturally occurring linear glycosaminoglycan that is composed of repeating polymeric disaccharides of D-glucuronic Acid and N-acetyl-D-glucosamine.
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