Happi Staff04.17.20
US Patent No. 10,568,827 B2 (Masaki Miyake, Motoyuki Suzuki, Tatsuya Ishihara, Toshio Ariyasu); Hayashibara Co. Ltd., Okayama, Japan, has patented a method for reducing skin yellowness and carbonyl protein already generated in the skin. It entails applying an external dermal agent comprising hesperetin and/or glycosyl hesperetin along with one or more members selected from the group consisting of maltose, maltotetraose, glycosyl trehalose, lactic acid, ferulic acid, glucuronic acid, acetic acid, sorbic acid and sodium glutamate as effective ingredients to the skin, wherein a ratio of carbonyl protein to no test agent control is measured and is reduced after applying the external dermal agent.