03.22.23
Burt’s Bees presented its latest research findings on the benefits of a topical bakuchiol-containing sunscreen in treating redness and pigmentation of photodamaged facial skin. The beauty brand, which is owned by The Clorox Company, also published research findings on a topical treatment in improving the appearance of post-inflammatory hyperpigmentation associated with acne. Both were developed for the American Academy of Dermatology 2023 Annual Meeting (AAD), which concluded yesterday in New Orleans, LA.
The findings highlight the tolerability of a bakuchiol-containing mineral, broad-spectrum sunscreen to effectively protect, firm, and smooth photodamaged skin, and the efficacy of a topical cream containing Glycyrrhiza glabra (licorice root), Curcuma longa (turmeric root), and Terminalia chebula in targeting hyperpigmentation, including dark spots and age spots
According to Hemali Gunt, PhD, head of clinical and scientific affairs at Burt’s Bees, the study on bakuchiol “utilizes robust imaging analysis for an objective measurement of changes to hyperpigmentation and redness, which is corroborated with dermatologist grading.”
The study of 27 female participants with clinically diagnosed sensitive skin and mild-to-moderate photodamaged skin (35–60 years) evaluated a photostable, broad-spectrum SPF 30 product with inorganic sunscreen actives and bakuchiol in a 12-week study using standardized, high-resolution facial photographs captured and analyzed for facial erythema (redness) and pigmentation.
Results showed a statistically significant decrease in skin pigmentation and redness from the baseline over the 12 weeks and a 20% improvement in skin hydration and maintenance of skin barrier function, according to the poster. Further, results confirmed that the nature-based, broad-spectrum sunscreen was effective in improving the health of photodamaged skin without causing the signs of irritation typically observed with retinol products.
“This is the first time we’ve seen a bakuchiol-containing formula demonstrate a decrease in erythema,” adds Raja Sivamani, MD, a board-certified dermatologist at Integrative Skin Science and Research and UC Davis, in California. “With this groundbreaking research, patients don’t have to compromise and choose between more even skin tone, the retinol-alternative benefits of bakuchiol, and an effective mineral sun protection.”
• Topical treatment with a cream containing Glycyrrhiza glabra, Curcuma longa, and Terminalia chebula improves the appearance of post-inflammatory hyperpigmentation associated with acne (Stanley B. Levy, Hemali B. Gunt, and Zoe D. Draelos).
A study of 39 female participants with moderate acne-induced, post-inflammatory hyperpigmentation (PIH) (Fitzpatrick skin type I-VI) (18–64 years) evaluated the effectiveness of a nature-based topical treatment containing Glycyrrhiza glabra (licorice root), Curcuma longa (turmeric root), and Terminalia chebula in reducing the appearance of PIH associated with acne.
Results showed a statistically significant improvement from baseline in skin brightness, smoothness, tone evenness, and overall skin condition, a reduction in melanin scores and corresponding pigmentation, and a 15% improvement in skin hydration and maintenance of skin barrier function. Results confirmed that treatment with the nature-based topical cream was clinically safe and effective in improving the appearance of acne-induced PIH, according to the poster.
“Hyperpigmentation disorders, including post-inflammatory hyperpigmentation and solar lentigines, are increasingly common conditions affecting most skin types and can have a significant impact on patient quality of life,” said Draelos in a statement. “In this research, the investigator, subject, and objective assessments all concurred to show an improvement in skin brightness with the formula, which incorporates three botanical tyrosinase inhibitors. Additionally, skin condition improved overall, including on the metrics of smoothness, evenness, pigmentation, and hydration.”
The studies are available online via ePoster.
The findings highlight the tolerability of a bakuchiol-containing mineral, broad-spectrum sunscreen to effectively protect, firm, and smooth photodamaged skin, and the efficacy of a topical cream containing Glycyrrhiza glabra (licorice root), Curcuma longa (turmeric root), and Terminalia chebula in targeting hyperpigmentation, including dark spots and age spots
According to Hemali Gunt, PhD, head of clinical and scientific affairs at Burt’s Bees, the study on bakuchiol “utilizes robust imaging analysis for an objective measurement of changes to hyperpigmentation and redness, which is corroborated with dermatologist grading.”
Posters
• Visible improvements in skin pigmentation and redness with topical bakuchiol-containing sunscreen using noninvasive clinical skin imaging technique in photodamaged facial skin (Hemali B. Gunt, Anastasia Shakhbazova, Adrianne Pan, Mincy Chakkalakal, and Raja Sivamani).The study of 27 female participants with clinically diagnosed sensitive skin and mild-to-moderate photodamaged skin (35–60 years) evaluated a photostable, broad-spectrum SPF 30 product with inorganic sunscreen actives and bakuchiol in a 12-week study using standardized, high-resolution facial photographs captured and analyzed for facial erythema (redness) and pigmentation.
Results showed a statistically significant decrease in skin pigmentation and redness from the baseline over the 12 weeks and a 20% improvement in skin hydration and maintenance of skin barrier function, according to the poster. Further, results confirmed that the nature-based, broad-spectrum sunscreen was effective in improving the health of photodamaged skin without causing the signs of irritation typically observed with retinol products.
“This is the first time we’ve seen a bakuchiol-containing formula demonstrate a decrease in erythema,” adds Raja Sivamani, MD, a board-certified dermatologist at Integrative Skin Science and Research and UC Davis, in California. “With this groundbreaking research, patients don’t have to compromise and choose between more even skin tone, the retinol-alternative benefits of bakuchiol, and an effective mineral sun protection.”
• Topical treatment with a cream containing Glycyrrhiza glabra, Curcuma longa, and Terminalia chebula improves the appearance of post-inflammatory hyperpigmentation associated with acne (Stanley B. Levy, Hemali B. Gunt, and Zoe D. Draelos).
A study of 39 female participants with moderate acne-induced, post-inflammatory hyperpigmentation (PIH) (Fitzpatrick skin type I-VI) (18–64 years) evaluated the effectiveness of a nature-based topical treatment containing Glycyrrhiza glabra (licorice root), Curcuma longa (turmeric root), and Terminalia chebula in reducing the appearance of PIH associated with acne.
Results showed a statistically significant improvement from baseline in skin brightness, smoothness, tone evenness, and overall skin condition, a reduction in melanin scores and corresponding pigmentation, and a 15% improvement in skin hydration and maintenance of skin barrier function. Results confirmed that treatment with the nature-based topical cream was clinically safe and effective in improving the appearance of acne-induced PIH, according to the poster.
“Hyperpigmentation disorders, including post-inflammatory hyperpigmentation and solar lentigines, are increasingly common conditions affecting most skin types and can have a significant impact on patient quality of life,” said Draelos in a statement. “In this research, the investigator, subject, and objective assessments all concurred to show an improvement in skin brightness with the formula, which incorporates three botanical tyrosinase inhibitors. Additionally, skin condition improved overall, including on the metrics of smoothness, evenness, pigmentation, and hydration.”
The studies are available online via ePoster.